Anti-opioid Effects of RFRP-3 on Magnocellular Neuron Activity in Morphine-naïve and Morphine-treated Female Rats
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چکیده
منابع مشابه
Effect of Jujube Extract on Acetylcholinesterase Activity and Oxidative Stress in Morphine-treated Male Rats
Background: One of the mechanisms associated with morphine neurotoxicity is oxidative stress. Jujube fruit extract may reduce oxidative stress due to its antioxidant properties. Objective: This study aims to investigate the protective effect of jujube fruit extract on the Acetylcholinesterase (AchE) activity and oxidative stress in the cortex and serum of morphine-treated male rats. Material...
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Introduction: Dependence on morphine and its complications are considered as a major health problem in the world; however, efforts to overcome this problem have failed due to the severity of drug dependence. Amygdala core nucleus (CeA) is one of the most important areas affecting the effects of morphine rewards. The GABAergic system in this nucleus; especially the GABAB receptors plays an impor...
متن کاملPlace Aversion by Morphine in Offspring Born of Female Morphine Administered Wistar Rats
This research was designed to study sexual differences in place conditioning induced by morphine in offspring born of female Wistar rats mated with drug-naïve males. Mothers were exposed to morphine during the 14th-16th days of gestational. Control dams were simply saline-injected. Female and male virgin offspring born of morphine-treated or saline-treated mothers were separately housed until b...
متن کاملClocinnamox distinguishes opioid agonists according to relative efficacy in normal and morphine-treated rats trained to discriminate morphine.
High doses of insurmountable antagonists or frequent administration of high doses of agonists are required to alter the potency of opioid agonists to produce discriminative stimuli. In the present study, insurmountable antagonism and repeated agonist treatment were combined to remove or disable a large enough proportion of mu-opioid receptors to alter the potency or maximal effect for four agon...
متن کاملPlace Aversion by Morphine in Offspring Born of Female Morphine Administered Wistar Rats
This research was designed to study sexual differences in place conditioning induced by morphine in offspring born of female Wistar rats mated with drug-naïve males. Mothers were exposed to morphine during the 14th-16th days of gestational. Control dams were simply saline-injected. Female and male virgin offspring born of morphine-treated or saline-treated mothers were separately housed until b...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2016
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2016-1374